… Brain muscarinic receptors are differently affected by AD and … tic sites on cholinoceptive
neurons are also involved. … binding sites in the frontal cortex of AD patients supports the …

… within the Northwestern Alzheimer's Disease Center have AD … the mediation of nicotinic
and muscarinic receptors. Molecular … cholinoceptive neurons may display downregulation of …

… We next evaluate whether muscarinic components of the cholinergic synapse are also …
Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer’s disease. …

… during the onset of Alzheimer's disease (AD). PreC layer III projection neurons contain
lysosomal hydrolase cathepsin D (CatD), a marker of neurons vulnerable to NFT pathology. Here …

… Alzheimer's disease (AD) is one of the most prevailing … As these neurons are cholinoceptive,
hence they are … due to neuron or synapse loss; decreased coupling of muscarinic M1 …

… together with intrinsic cholinoceptive neurons. In contrast to high … antibody WF6 in the human
frontal cortex from middle to old age.… cortical neurons contain both nicotinic and muscarinic …

… in ChAT F activity in the CSF of patients following treatment with a ChEI. These findings
may … of the cholinergic neurons as well as the down-stream cholinoceptive neurons. In other …

… cases and those with pathologic Alzheimer's disease (AD). … neurons, but not ChAT,
suggests that they are cholinoceptive … (∼70%) of the muscarinic m-2 receptor, a postsynaptic …

… in the myelination of neurons [80]. AChE and BChE also impact muscarinic and nicotinic …
of nicotinic cholinoceptive neurons, as well as improved CNS cholinergic signaling [87]. …

… prefrontal cortex excitatory networks that underlie working memory function [28, 29]. Moreover,
… Visualization of cholinoceptive neurons in the rat neocortex: Colocalization of muscarinic …